Cortical GABAergic Neural Circuits.
نویسندگان
چکیده
منابع مشابه
Genetic dissection of GABAergic neural circuits in mouse neocortex
Diverse and flexible cortical functions rely on the ability of neural circuits to perform multiple types of neuronal computations. GABAergic inhibitory interneurons significantly contribute to this task by regulating the balance of activity, synaptic integration, spiking, synchrony, and oscillation in a neural ensemble. GABAergic interneurons display a high degree of cellular diversity in morph...
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Affect is the fundamental neuropsychological state combining valueand arousal-related processes underpinning emotion and mood. A major goal of the emerging field of affective science is to explain the mechanisms of valuation within the brain. A core network of brain activity is seen across mammals in response to appetitive or aversive stimuli, and appears to be largely independent of stimulus m...
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The mature neocortex contains many different classes of GABAergic inhibitory interneurons, distributed, with some degree of selectivity, through six layers, and through many different regions. Some of the events in the early lives of these neurones that may determine their ultimate destination, their maturation and their selective innervation of targets appropriate for each subtype, are discuss...
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In the cerebellum and basal ganglia, projection neurons are GABAergic; but in the cerebral cortex, there has been a historically strong dichotomy between glutamatergic projection neurons and GABAergic local circuit neurons. While this dichotomy is overwhelmingly valid, it is now clear that a small population of longdistance projecting GABAergic neurons occurs in primates, as well as in cats and...
متن کاملGABAergic circuits control spike-timing-dependent plasticity.
The spike-timing-dependent plasticity (STDP), a synaptic learning rule for encoding learning and memory, relies on relative timing of neuronal activity on either side of the synapse. GABAergic signaling has been shown to control neuronal excitability and consequently the spike timing, but whether GABAergic circuits rule the STDP remained unknown. Here we show that GABAergic signaling governs th...
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ژورنال
عنوان ژورنال: The Brain & Neural Networks
سال: 1998
ISSN: 1883-0455,1340-766X
DOI: 10.3902/jnns.5.171